We invite you to a special session as part of GLBIO 2021
Comprehensive understanding of a gene’s function requires going beyond a high-level annotation of its molecular function and biological process to a more detailed characterization of its specific role in the relevant signaling, epigenetic or enzymatic context as well as its interactions with DNA and other proteins. An integrative approach across species or conditions, combining omics with physiology-based approaches, can advance understanding and potentially lead to testable hypotheses. We are particularly excited about bioinformatics research that adapts computational tools and extends data infrastructures for model organisms to investigate phenotypes of non-model organisms, using integrative and systems-based approaches to overcome the relative lack of data in the latter.
To invite a diverse set of research presentations on this topic, we propose splitting the topic into model and non-model organisms. We believe that the core community that attends GLBIO is already very interested in the genotype to phenotype problem as it relates to human health and disease, and may contribute some interesting talks for part I. Non-model organisms and in particular, organisms whose importance is outside biomedical applications, have not been historically well-represented in this community, and we are excited to invite interesting speakers and bring this new area to part II of our session and this conference.